1. Emotion - methods for mood & anxiety disorders
(Neurohacking/Theory & Research)

... fear extinction by D-cycloserine is mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase cascades and requires de novo protein synthesis in basolateral nucleus of amygdala. Neuroscience ...

2. Emotion - disorders of emotion
(Neurohacking/Theory & Research)

... and its receptor, the tyrosine kinase TrkB, does not seem to cause depressive behaviors, but does hamper the effect of antidepressant drugs. Thus, BDNF may be a target of antidepressants, but not the sole ...

3. Memory - memory editing update, 2004-2011
(Neurohacking/Theory & Research)

... for large-scale long-term memory storage in the brain was recently identified as the persistent action of protein kinase Mzeta (PKMzeta). The sensorimotor cortex has a role in procedural learning. Previous ...

4. Physiological methods - Epigenetics - Hacking the genome
(Neurohacking/Methods & Technology)

... and memory/learning/LTP   The process of putting stuff into long term memory requires gene transcription factors in the production of new proteins, specifically kinases that affect the rate of ...

5. Anatomy & physiology - Neurogenesis
(Neurohacking/Theory & Research)

...  cdk5 is a kinase, a protein whose job is to phosphorylate and thus alter the behavior of other proteins. While this study did not address the mechanism through which cdk5 acts, the authors suggest a ...

6. Physiological methods - Longevity and Epigenetic Modification (Intermediate Level NH)
(Neurohacking/Methods & Technology)

... Genome Project Had a Working Base Approximately 55 genes had been identified that could extend longevity when altered. These include an insulin-like receptor (daf-2) and a phosphatidylinositol 3-OH kinase ...

7. ICMM 10 Memory Editors (enhancing & wiping)
(Workshop/I've Changed My Mind)

... ion channels (e.g., NMDA, or nicotine acetylcholine receptors). Once in the cell, calcium ions bind to protein kinases, the most important of which is probably Calmodulin (CaM). This starts a complex series ...

8. ICMM 16 Advanced Applications Level 1 (hacking pain)
(Workshop/I've Changed My Mind)

... fire repetitively, leading to activation of NMDA receptors, kinase release affecting gene transcription, and consequently a change in the nociceptors themselves which makes them more sensitive to subsequent ...